Cancer is currently the main cause of death in medical clinical practice.Hedyotis diffusa Willd.is a plant species belonging to the Hedyotis Linn.Rubiaceae family and is widely used in treatment of malignant tumors.Hedyotidis Diffusae Herba can inhibit the proliferation of tumor cells,induce programmed cell death,inhibit the invasion and migration of tumor cells,inhibit tumor angiogenesis,increase chemotherapy drug sensitivity,and regulate the body's immune system.This article reviews the research progress on anti-tumor mechanism of Hedyotidis Diffusae Herba,in order to provide a basis for its clinical application in anti-tumor therapy.
Hedyotidis Diffusae Herbaantitumorcell proliferationprogrammed cell deathcell invasiontumor angiogenesischemotherapy drug sensitivitybody's immune system