Clinical study on Yaobitong Capsules combined with diosming in treatment of lumbar spinal stenosis
Objective To investigate the clinical study of Yaobitong Capsules combined with Diosming Tablets in treatment of lumbar spinal stenosis. Methods 94 Patients with lumbar spinal stenosis who visited Zhangjiakou First Hospital from June 2021 to May 2024 were selected and divided into control group and treatment group using a random number table method,with 47 patients in each group. The patients in the control group were po administered with Diosmin Tablets after lunch and dinner,1 tablets/time. The patients in the treatment group were po administered with Yaobitong Capsules on the basis of the control group,3 grains/time,3 times daily. Two groups of patients were treated continuously for 4 weeks. The clinical efficacy,lumbar function,and serum indexes of the two groups were compared. Results After treatment,the total effective rate was 95.74％ in the treatment group,and 82.98％ in the control group,and the difference was significant between two groups (P<0.05). After treatment,ODI scores of the two groups was significantly decreased (P<0.05),and ODI score of the treatment group was lower than that of the control group (P<0.05). After treatment,the serum levels of IL-1α,MMP-3,and IL-18 in two groups were decreased (P<0.05),and the serum levels of IL-1α,MMP-3,and IL-18 in the treatment group were lower than those in the control group (P<0.05). Conclusion Yaobitong Capsules combined with Diosming Tablets can improve the curative effect of lumbar spinal stenosis,improve the function of lumbar spine and reduce the inflammatory response.
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