Research progress on pharmacological effects of matrine in treatment of skin diseases
Skin diseases can cause varying degrees of itching,pain,affect aesthetics,and seriously affect the quality of life of patients. Matrine is an alkaloid from Sophorae Flavescentis Radix,which has various pharmacological effects. Matrine can treat various skin diseases through multiple pathways and targets,such as regulating immune response,reducing inflammatory damage,enhancing cell autophagy,promoting cell apoptosis,relieving pain and itching,and resisting skin fibrosis. This article summarizes the pharmacological research progress of matrine in treatment of skin diseases,providing reference for the clinical application of matrine.
matrineskin diseaseimmune responseinflammatory damagecell autophagycell apoptosisrelieving pain and itchingskin fibrosis