Clinical study on Shenqu Xiaoshi Oral Liquid combined with Compound Digestive Enzyme Capsules in treatment of children with anorexia
Objective To investigate the effect of Shenqu Xiaoshi Oral Liquid combined with Compound Digestive Enzyme Capsules in treatment of children with anorexia.Methods 94 Children with anorexia who received treatment at Beijing Children's Hospital,Capital Medical University from June 2023 to March 2024 were selected and divided into two groups using computer randomization with 47 cases in each group.Children in control group took Compound Digestive Enzyme Capsules orally 30 min before meals,2 capsules/time,3 times daily.Children in the treatment group took Shenqu Xiaoshi Oral Liquid orally on the basis of the control group,5 mL each time at the age of 3 to 5 years,and 10 mL each time at the age of 5 to 13 years,3 times daily.Children in both groups were evaluated after 2 weeks of treatment.The total effective rate,body mass,diet,and serum factor levels were compared between two groups.Results Compared with the total effective rate of 80.85%in the control group,the total effective rate of 95.74%in the treatment group was higher,and the difference between groups was significant(P<0.05).The body mass of the two groups after treatment was higher than those before treatment,but the feeding time was lower than before treatment(P<0.05).After treatment,the body mass of the treatment group was higher than that of the control group,but the feeding time of the treatment group was lower than that of the control group(P<0.05).LEP after treatment was lower than that before treatment,but NPY and β-EP in the treatment group were higher than those before treatment(P<0.05).LEP in the treatment group was lower than that in the control group after treatment,but NPY and β-EP were higher than those in the control group after treatment(P<0.05).Conclusion Shenqu Xiaoshi Oral Liquid combined with Compound Digestive Enzyme Capsules can provide therapeutic effect for children with anorexia,improve body weight,reduce eating time,and improve neurotransmitter release.
NETL
NSTL
万方数据
