首页|湿润烧伤膏联合复方磺胺嘧啶锌凝胶治疗头面部烧伤的临床研究

湿润烧伤膏联合复方磺胺嘧啶锌凝胶治疗头面部烧伤的临床研究

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目的 探讨湿润烧伤膏联合复方磺胺嘧啶锌凝胶治疗头面部烧伤的临床疗效。方法 选择2020年 3 月—2023 年 12月在太原钢铁(集团)有限公司总医院就诊的 82 例头面部烧伤患者,按随机数字表法将所有患者分为对照组和治疗组,每组各 41 例。对照组涂抹复方磺胺嘧啶锌凝胶厚度 0。15~0。35 mm,1 次/d;治疗组涂抹复方磺胺嘧啶锌凝胶与湿润烧伤膏1∶3 混合物厚度约1 mm。两组持续治疗 14 d。评估两组的总有效率、主观疼痛程度和凝血功能指标。结果 治疗组的总有效率为 82。93%,对照组的总有效率为 63。41%,两组组间比较差异显著(P<0。05)。治疗后,两组的视觉模拟评分法(VAS)评分均显著降低(P<0。05),且治疗组的VAS评分较对照组更低(P<0。05)。治疗后,两组的纤维蛋白原(FIB)、D-二聚体(D-D)水平低于治疗前,血小板计数(PTL)水平高于治疗前(P<0。05);治疗组的FIB、D-D水平低于对照组,PTL水平高于对照组(P<0。05)。结论 湿润烧伤膏联合复方磺胺嘧啶锌凝胶可提高头面部烧伤的临床疗效,进一步减轻疼痛程度,改善凝血功能。
Clinical study on with Shirun Shaoshang Ointment combined with Compound Sulfadiazine Zinc Gel in treatment of head and facial burns
Objective To investigate the efficacy of Shirun Shaoshang Ointment combined with Compound Sulfadiazine Zinc Pingment in treatment of head and facial burns.Methods 82 Patients with head and facial burns in Taiyuan Iron and Steel(Group)Co.,Ltd.,General Hospital from March 2020 to December 2023 were divided into control and treatment group by random number table method,with 41 cases per group.Patients in the control group were treated with Compound Sulfadiazine Zinc Gel with a thickness of 0.15-0.35 mm,once daily.Patients in the treatment group applied a 1:3 mixture of Compound Sulfadiazine Zinc Gel and Shirun Shaoshang Ointment with a thickness of about 1 mm.Patients in both groups were treated for 14 d.The total effective rate,subjective pain degree,and coagulation function of the two groups were evaluated.Results The total effective rate was 82.93%in the treatment group,and 63.41%in the control group,and the difference between two groups was significant(P<0.05).After treatment,VAS scores of two groups were significantly decreased(P<0.05),and VAS scores of the treatment group were lower than those in the control group(P<0.05).After treatment,FIB and D-D levels of two groups were lower than those before treatment,but PTL levels of two groups were higher than those before treatment(P<0.05).FIB and D-D levels in the treatment group were lower than those in the control group,but PTL levels were higher than those in the control group(P<0.05).Conclusion The combination of Shirun Shaoshang Ointment and Compound Sulfadiazine Zinc Gel can improve the efficacy of head and facial burns,further reduce pain,and improve coagulation function.

Shirun Shaoshang OintmentCompound Sulfadiazine Zinc Gelhead and facial burnsVAS scoreFIBD-DPTL

陈越、孟艳斌、白培懿、任锋

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太原钢铁(集团)有限公司总医院 烧伤二科,山西 太原 030009

山西中医药大学,山西 太原 030619

湿润烧伤膏 复方磺胺嘧啶锌凝胶 头面部烧伤 VAS评分 纤维蛋白原 D-二聚体 血小板计数

山西省卫生计生委科研课题项目

2015104

2024

现代药物与临床
天津药物研究院,中国药学会

现代药物与临床

CSTPCD
影响因子:1.179
ISSN:1674-5515
年,卷(期):2024.39(10)
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