Clinical study of Yiqing Tablets combined with ornidazole in treatment of pericoronitis of wisdom teeth
Objective To investigate the efficacy of Yiqing Tablets combined with Ornidazole Tablets in treatment of pericoronitis of wisdom teeth.Methods A total of 112 patients with pericoronitis of wisdom teeth treated in Affiliated Stomatology Hospital of Anhui Medical University from January 2022 to October 2023 were selected and divided into control group and treatment grou p according to random number table method,with 56 cases in each group.Patients in the control group were given Ornidazole Tablets,1 tablet/time,once daily.Patients in the treatment group were po administered with Yiqing Tablets on the basis of the control group,4 tablet/time,three times daily.Both groups were treated for 10 d.The clinical effects of the two groups were observed,and the changes of visual analogue scale(VAS)scores,Oral health Impact Scale(OHIP-14)scores,pericoronitis related indicators and gingival crevicular fluid inflammatory factors before and after treatment were compared between two groups.Results After treatment,the total effective rate of treatment group was 96.43%,which was significantly higher than that of control group 82.14%(P<0.05).After treatment,VAS and OHIP-14 scores in both groups were significantly decreased(P<0.05),and the scores in the treatment group were significantly decreased after treatment(P<0.05).After treatment,the scores of gingival index(GI),plaque index(PLI)and gingival crevicular bleeding index(SBI)were significantly decreased in two groups(P<0.05).After treatment,the related indexes of pericoronitis in the treatment group were significantly decreased(P<0.05).After treatment,the levels of procalcitonin(PCT)and C-reactive protein(CRP)in gingival crevicular fluid were significantly decreased in two groups(P<0.05).After treatment,the levels of PCT and CRP in gingival crevicular fluid in treatment group were lower than those in control group(P<0.05).Conclusion Yiqing Tablets combined with ornidazole has significant clinical effect in treatment of pericoronitis of wisdom teeth,and can reduce the pain,improve the symptoms of pericoronitis and the quality of life,which can inhibit the inflammatory response.
Yiqing TabletsOrnidazole Tabletspericoronitis of wisdom teethVAS scoreOHIP-14 scoreGIPLISBIPCTCRP
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