Advances in anti-VEGF-targeted drugs combined with immunotherapy in treatment of breast cancer
Breast cancer,as the first common malignant tumor in women,seriously affects the quality of life of female patients.Vascular endothelial growth factor(VEGF)has been identified as the key factor to induce tumor angiogenesis.At present,there are many anti-VEGF-targeted drugs for the treatment of breast cancer.On the other hand,the emergence of immunotherapy is a major breakthrough in the treatment of malignant tumors.Anti-angiogenesis drugs and immunotherapy are a reasonable choice in treatment of breast cancer.This article summarized the research progress of anti-VEGF-targeted drugs combined with immune checkpoint inhibitors,tumor vaccines,therapeutic antibodies in the treatment of breast cancer.
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