Research progress on the pharmacological effects of emodin in prevention and treatment of acute pancreatitis
Acute pancreatitis is the most common gastrointestinal acute and severe disease,but its incidence rate and mortality are high due to the lack of specific drugs.Emodin is the main active ingredient in Rhei Radix et Rhizoma and has various pharmacological effects.Emodin can control the progression of acute pancreatitis and alleviate pancreatic tissue damage by reducing inflammation response,decreasing pancreatic tissue cell apoptosis,protecting intestinal barrier function,reducing oxidative stress response,regulating immune balance,and lowering digestive enzyme secretion through multiple pathways and targets.This article summarizes the research progress on the pharmacological effects of emodin in prevention and treatment of acute pancreatitis,providing reference for the clinical application of emodin.
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