Research progress on pharmacological action of Dioscorea nipponica saponins in preventing and treating aplastic anemia
Aplastic anemia is a blood immune dysfunction characterized by a decrease in whole blood cells and bone marrow failure,and immunosuppressive therapy is the most commonly used treatment method.Dioscorea nipponica saponins has a structure similar to steroid hormones and has multiple pharmacological effects.Dioscorea nipponica saponins can enhance bone marrow proliferation activity,regulate immune balance,inhibit bone marrow cell apoptosis,prevent bone marrow cell lipidation,promote angiogenesis,reduce inflammatory response to promote bone marrow hematopoietic function recovery,increase the number of nuclear cells,and restore blood count indicators.This article summarizes the pharmacological research progress of Dioscorea nipponica saponins in preventing and treating aplastic anemia,providing support for the clinical application of Dioscorea nipponica saponins.
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