Objective To explore the clinical efficacy of Shujin Tongluo Granules combined with Pregabalin Capsules in treatment of cervical spondylotic radiculopathy.Methods 94 Patients with cervical spondylotic radiculopathy admitted to Jilin University Hospital from August 2022 to August 2024 were divided into control group and treatment group using a random number table method,with 47 patients in each group.The control group patients took Pregabalin Capsules,one capsule each time twice daily.On the basis of the control group,patients in the treatment group were orally administered Shujin Tongluo Granules,1 bag each time,3 times daily.The efficacy,cervical spine function,pain level,electromyographic indicators,and serum indicators between two groups were compared.Results The total effective rate of the treatment group was 93.62%,while the total effective rate of the control group was 80.85%,with significant differences between the groups(P<0.05).NDI scores and NRS in the upper limbs and shoulder neck of both groups were decreased(P<0.05),and NDI scores and NRS of the upper limbs and shoulder neck in the treatment group was lower than those of the control group(P<0.05).After treatment,the F-wave conduction velocity of the ulnar nerve and median nerve in both groups were increased(P<0.05),and these factors in the treatment group was higher than those in the control group(P<0.05).The levels of TNF-α,IL-1β,and IL-18 in both groups were decreased(P<0.05),and levels of TNF-α,IL-1β,and IL-18 in the treatment group were lower than those of the control group(P<0.05).Conclusion The combination of Shujin Tongluo Granules and Pregabalin Capsules can improve the therapeutic effect of cervical spondylotic radiculopathy,further improve cervical function and reduce pain,reduce inflammatory response,improve nerve transmission speed.
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