Clinical study on Potassium Sodium Pehydroandroandrographolide Succinate for injection(lyophilized)combined with ribavirin in treatment of viral pneumonia
Objective To explore the therapeutic effect of Potassium Sodium Pehydroandroandrographolide Succinate for injection(lyophilized)combined with Ribavirin Injection in treatment of viral pneumonia Methods 80 Patients with viral pneumonia admitted to Suzhou Ninth People's Hospital from May 2022 to May 2023 were divided into a control group(n=40 cases)and a treatment group(n=40 cases)using a random number table method.The control group received intravenous infusion of Ribavirin Injection,with each dose of 500 mg added to 500 mL 5%glucose injection,twice daily.On the basis of control group,the treatment group received Potassium Sodium Pehydroandroandrographolide Succinate for injection(lyophilized),with each dose of 400 mg added to 250 mL 5%glucose injection once daily.Both groups were treated for 5 d.The clinical efficacy,symptom relief times,and inflammatory index levels between the two groups were compared.Results After treatment,the total effective rate of patients in the treatment group(97.50%)was higher than 80.00%in the control group(P<0.05).After treatment,the improvement time of fever,sore throat,and cough in the treatment group was shorter than those of the control group(P<0.05).After treatment,the levels of serum IL-6,TNF-α,and CRP in the two groups were lower than those before treatment(P<0.05),and the levels of serum IL-6,TNF-α,and CRP in the treatment group were lower than those in the control group(P<0.05).Conclusion Potassium Sodium Pehydroandroandrographolide Succinate for injection(lyophilized)combined with Ribavirin Injection has a definite therapeutic effect on viral pneumonia,which can effectively alleviate clinical symptoms and inflammatory reactions.
Potassium Sodium Pehydroandroandrographolide Succinate for injection(lyophilized)Ribavirin Injectionviral pneumoniaimprovement time of feverimprovement time of soreimprovement time of coughIL-6TNF-αCRP
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