Research progress of polydatin in prevention and treatment of diabetes nephropathy
Diabetes nephropathy is one of the major complications of type 2 diabetes,and the main cause of death in patients with end-stage renal disease and renal failure.Polydatin is an active ingredient extracted from Polygoni Cuspidati Rhizoma,which can play a role in preventing and treating diabetes nephropathy by reducing inflammatory damage of renal tissue,reducing oxidative stress response,delaying renal tissue fibrosis,preventing renal tissue cells apoptosis,and reducing blood sugar.This article summarized the research progress of polydatin in treatment of diabetes nephropathy,analyzed its mechanism of action,and provided a basis for the clinical study of polydatin in treatment of diabetes nephropathy.
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