首页|丹参酮ⅡA改善心肌梗死的研究进展

丹参酮ⅡA改善心肌梗死的研究进展

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心肌梗死已成为威胁人类健康的重要疾病之一。丹参酮ⅡA是从丹参中提取的有效成分,具有多种药理活性,可通过舒张血管、延缓心肌纤维化进程、抑制心肌细胞凋亡、减轻炎症反应、降低氧化应激反应、促进新生血管形成发挥治疗心肌梗死的作用。综述了丹参酮ⅡA改善心肌梗死的药理作用研究进展,希望为丹参酮ⅡA的临床应用提供参考。
Research progress on improvement of myocardial infarction by tanshinone IIA
Myocardial infarction has become one of the important diseases threatening human health.Tanshinone IIA is an active ingredient extracted from Salviae Miltiorrhizae Radix et Rhizoma,with various pharmacological activities.Tanshinone IIA can treat myocardial infarction by dilating blood vessels,delaying the progression of myocardial fibrosis,inhibiting myocardial cell apoptosis,reducing inflammatory response,lowering oxidative stress response,and promoting neovascularization.This article reviews the pharmacological research progress of tanshinone IIA in improving myocardial infarction,hoping to provide reference for the clinical application of tanshinone IIA.

tanshinone IIAmyocardial infarctiondilate blood vesselmyocardial fibrosiscell apoptosisinflammatory responseoxidative stress responseneovascularization

蒋曼、安素、何璐瑶

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重庆医科大学附属大足医院 心血管内科,重庆 402360

重庆医科大学附属大足区人民医院 心内科,重庆 402360

丹参酮ⅡA 心肌梗死 舒张血管 心肌纤维化 细胞凋亡 炎症反应 氧化应激反应 新生血管形成

2024

现代药物与临床
天津药物研究院,中国药学会

现代药物与临床

CSTPCD
影响因子:1.179
ISSN:1674-5515
年,卷(期):2024.39(12)