Value of high b-value diffusion-weighted imaging in the diagnosis of hyperacute phase of acute ischemic stroke
Objective To explore the application value of high b-value diffusion-weighted imaging(DWI)and apparent diffu-sion coefficient(ADC)in the diagnosis of hyperacute phase of acute ischemic stroke(AIS),and provide a reference for clini-cal treatment.Methods A total of 34 patients with AIS in the hyperacute phase(onset time<6 hours)who were clinically diagnosed and treated with recovery or improvement from June 2020 to February 2023 at the Beibei Hospital of Traditional Chinese Medicine were selected as the study participants.All 34 patients underwent high b-value(b-value = 2000 s/mm2)and conventional b-value(b-value = 1000 s/mm2)DWI scans.The DWI images were divided into a high b-value group and a conventional b-value group,and the DWI imaging features of the two groups were analyzed.Quantitative analysis was per-formed on the ADC maps.Results The number of lesions detected in the high b-value and conventional b-value groups was 98 and 74,respectively.T1-weighted images showed equal or slightly low signal,and T2-weighted images and T2-Flair im-ages showed equal or slightly high signal,with no specificity.The DWI images of the lesions in the high b-value group showed a moderate to high signal,while those in the conventional b-value group showed a mild to moderate high signal.Mo-reover,the lesion boundaries were clearer in the high b-value group.The comparison of ADC values between the high b-val-ue and conventional b-value groups showed that the ADC values in the lesion area were significantly lower in the high b-value group(P<0.05).The ADC values in the symmetrical area of the unaffected side were also significantly lower in the high b-value group(P<0.05).The comparison of ADC values at the same b-value showed statistically significant differences in ADC values between the lesion area and the symmetrical area of the unaffected side in both groups(P<0.05).The sensitiv-ity of the high b-value group was 100.0%,while the specificity was 82.4%.In the conventional b-value group,the sensitiv-ity was 100.0%,while the specificity was 76.5%.The signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)were significantly higher in the high b-value group than in the conventional b-value group(P<0.05).Conclusion In clinical practice,the use of high b-value DWI scanning can raise the detection rate of AIS lesions in the hyperacute phase and pro-mote the quality of lesion imaging.Therefore,high b-value DWI has a higher diagnostic value for hyperacute phase AIS than conventional b-value DWI,which may hold promise for a wider clinical application.
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