Postoperative adjuvant therapy for HCC patients with microvascular invasion:current status and prospects
Primary hepatocellular carcinoma is a common malignant tumor worldwide,and surgical resection remains the first choice of treatment.However,microvascular invasion(MVI)as an independent risk factor affects the survival of pa-tients after surgery.This article introduces the effect of postoperative MVI positive on prognoses and reviews several adju-vant therapy methods commonly used to prevent postoperative recurrence and improve the survival of patients undergoing hepatectomy,including radiotherapy,transcatheter arterial chemoembolization(TACE),hepatic arterial infusion chemo-therapy(HAIC),targeted therapy,immunotherapy,antiviral,and nutritional support therapy.The therapeutic effects of various therapies on MVI positive patients were reviewed.Here,we concluded that most treatments have shown promise,but efficacy and target populations need to be further explored,combined therapy may be the direction of postoperative adju-vant therapy in the future.
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