首页|中医药治疗慢性阻塞性肺疾病经济学评价研究的质量评价

中医药治疗慢性阻塞性肺疾病经济学评价研究的质量评价

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目的 系统回顾中医药治疗慢性阻塞性肺疾病(COPD)经济学评价研究相关文献,分析研究中存在的主要问题并提出建议,为规范药物经济学评价研究提供借鉴.方法 计算机检索中国知网、维普网和PubMed等数据库自建库至2023年8月1日中医药治疗COPD经济学评价研究相关文献.对纳入文献从研究角度、成本类型和分析方法等方面进行描述性分析,并评价文献质量.结果 共纳入9篇文献,均为高质量文献(标准符合率≥75%).纳入研究均表明中医药治疗COPD具有经济性.干预措施包括药物治疗和中医特色治疗.仅3项研究明确了研究角度.仅2项研究的成本类型为直接成本和间接成本,多数研究为直接成本.仅3项研究的分析方法为成本效用分析,多数研究为成本效果分析.仅3项研究的产出指标为健康效用值,多数研究为有效率.仅3项研究为模型法研究,使用了 Markov或联合决策树模型,模型参数均源于文献.所有研究均进行了单因素敏感性分析.结论 现有的中医药治疗COPD经济学评价研究数量较少,且存在研究角度不明确、成本测算范围小、分析方法与健康产出指标选择不恰当、研究时限普遍较短、模型法运用较少的问题,建议未来开展的中医药治疗COPD经济学评价研究结合我国实际情况对评价方法和工具进行完善,积极且规范化开展药物经济学评价研究,为COPD治疗方案的优化提供科学客观的决策依据.
Quality assessment of economic evaluation studies on Traditional Chinese Medicine treatment for chronic obstructive pulmonary disease
Objective This paper aims to systematically review economic evaluation studies on traditional Chinese medicine(TCM)treatment for chronic obstructive pulmonary disease(COPD),analyze the main issues in these studies,and provide recommendations for standardizing economic evaluation research on medication.Methods Chinese databases(CNKI,VIP)and international database(PubMed)were searched from the inception of the databases to August 1,2023,for economic e-valuation studies on TCM treatment for COPD.Descriptive analysis was conducted on the included literature from the per-spectives of research design,cost types,and analysis methods,and the quality of the literature was evaluated.Results A total of 9 articles were included,all of which were of high quality(compliance rate 75%).The included studies all indica-ted the cost-effectiveness of TCM treatment for COPD.The intervention measures included medication therapy and TCM characteristic treatment.Only 3 studies explicitly stated their research perspectives.Only 2 studies considered both direct and indirect costs,while most studies focused on direct costs.Only 3 studies used cost-utility analysis as the analysis meth-od,while most studies used cost-effectiveness analysis.Besides,only 3 studies used health utility values as the outcome measure,while most studies used efficacy measures.Only 3 studies employed modeling methods,using Markov or joint de-cision tree models,and the model parameters were derived from the literature.All studies performed one-way sensitivity a-nalysis.Conclusion The number of existing economic evaluation studies on TCM treatment for COPD is limited,and there are issues such as unclear research perspectives,limited scope of cost calculation,inappropriate choice of analysis methods and health outcome measures,generally short study duration,and limited use of modeling methods.Here,we recommen-ded that future economic evaluation studies on TCM treatment for COPD should improve evaluation methods and tools based on the actual situation in China,actively and standardly conduct medication economic evaluation research,and provide accu-rate decision-making support for optimizing COPD treatment strategies.

PharmacoeconomicsTraditional Chinese medicineChronic obstructive pulmonary diseaseSystematic review

刘紫萱、朱嘉欣、何素珍、蒙晓、陈一帆、豆志州、魏理

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广州医科大学附属第一医院药学部,广州 510120

广州医科大学药学院,广州 511436

药物经济学 中医药 慢性阻塞性肺疾病 系统评价

广东省基础与应用基础研究基金市校(院)联合项目

2021A1515220096202201020448

2024

保健医学研究与实践
西南大学

保健医学研究与实践

CSTPCD
影响因子:0.512
ISSN:1673-873X
年,卷(期):2024.21(2)
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