Quality assessment of economic evaluation studies on Traditional Chinese Medicine treatment for chronic obstructive pulmonary disease
Objective This paper aims to systematically review economic evaluation studies on traditional Chinese medicine(TCM)treatment for chronic obstructive pulmonary disease(COPD),analyze the main issues in these studies,and provide recommendations for standardizing economic evaluation research on medication.Methods Chinese databases(CNKI,VIP)and international database(PubMed)were searched from the inception of the databases to August 1,2023,for economic e-valuation studies on TCM treatment for COPD.Descriptive analysis was conducted on the included literature from the per-spectives of research design,cost types,and analysis methods,and the quality of the literature was evaluated.Results A total of 9 articles were included,all of which were of high quality(compliance rate 75%).The included studies all indica-ted the cost-effectiveness of TCM treatment for COPD.The intervention measures included medication therapy and TCM characteristic treatment.Only 3 studies explicitly stated their research perspectives.Only 2 studies considered both direct and indirect costs,while most studies focused on direct costs.Only 3 studies used cost-utility analysis as the analysis meth-od,while most studies used cost-effectiveness analysis.Besides,only 3 studies used health utility values as the outcome measure,while most studies used efficacy measures.Only 3 studies employed modeling methods,using Markov or joint de-cision tree models,and the model parameters were derived from the literature.All studies performed one-way sensitivity a-nalysis.Conclusion The number of existing economic evaluation studies on TCM treatment for COPD is limited,and there are issues such as unclear research perspectives,limited scope of cost calculation,inappropriate choice of analysis methods and health outcome measures,generally short study duration,and limited use of modeling methods.Here,we recommen-ded that future economic evaluation studies on TCM treatment for COPD should improve evaluation methods and tools based on the actual situation in China,actively and standardly conduct medication economic evaluation research,and provide accu-rate decision-making support for optimizing COPD treatment strategies.
PharmacoeconomicsTraditional Chinese medicineChronic obstructive pulmonary diseaseSystematic review