保健医学研究与实践2024,Vol.21Issue(3) :82-88.DOI:10.11986/j.issn.1673-873X.2024.03.14

DCE-MRI在乳腺良性病变与乳腺癌诊断中的应用价值

Application value of dynamic contrast-enhanced MR1 in the diagnosis of benign breast lesions and breast cancer

李崇 杨勇 徐成春 陈兴友 黎敏 任逢春
保健医学研究与实践2024,Vol.21Issue(3) :82-88.DOI:10.11986/j.issn.1673-873X.2024.03.14

DCE-MRI在乳腺良性病变与乳腺癌诊断中的应用价值

Application value of dynamic contrast-enhanced MR1 in the diagnosis of benign breast lesions and breast cancer

李崇 1杨勇 1徐成春 1陈兴友 1黎敏 1任逢春2
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作者信息

  • 1. 四川省西昌市人民医院放射科,四川 西昌 615000
  • 2. 成都中医药大学附属医院放射科,成都 610000
  • 折叠

摘要

目的 探讨磁共振成像动态增强扫描(DCE-MRI)在乳腺良性病变与乳腺癌诊断中的应用价值.方法 选取2021年1月-2023年12月四川省西昌市人民医院收治的289例乳腺疾病患者作为本次研究对象.以术后病理检查结果为金标准,分析弥散加权成像(DWI)、DCE-MRI对乳腺良性病变与乳腺癌的诊断价值,并比较乳腺良性病变与乳腺癌患者表观扩散系数(ADC)值、DCE-MRI影像学表现.结果 病理结果显示,289例乳腺疾病患者中乳腺良性病变212例,占73.36%,乳腺癌77例,占26.64%.乳腺良性病变组、乳腺癌组患者的ADC值、病灶边缘情况、病灶形状情况、时间-信号强度(TIC)类型、强化特征情况比较,差异均有统计学意义(P<0.05).DWI诊断乳腺良性病变188例,乳腺癌101例,诊断准确率为72.66%;DCE-MRI诊断乳腺良性病变179例,乳腺癌110例,诊断准确率为66.44%;二者联合诊断乳腺良性病变203例,乳腺癌86例,诊断准确率为87.54%(P<0.05).DWI、DCE-MRI及二者联合诊断乳腺良性病变与乳腺癌的曲线下面积(AUC)分别为 0.871、0.806、0.911,特异度分别 92.21%、89.61%、90.91%,灵敏度分别为 85.85%、80.66%、92.45%.结论 DWI、DCE-MRI在乳腺良性病变与乳腺癌的鉴别诊断中具有较高的临床价值,且二者联合可提高诊断准确率.

Abstract

Objective To explore the application value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in diagnosing benign breast lesions and breast cancer.Methods A total of 289 patients with breast diseases treated at the Xichang People's Hospital from January 2021 to December 2023 were selected for this study.Using postoperative pathologi-cal results as the gold standard,the diagnostic value of DWI and DCE-MRI for benign breast lesions and breast cancer was analyzed,and the apparent diffusion coefficient(ADC)values and DCE-MRI imaging features of benign and malignant breast lesions were compared.Results Pathological results showed that among 289 breast disease patients,212 had benign lesions(73.36% )and 77 had breast cancer(26.64% ).Significant differences were found in ADC values,lesion margins,lesion shapes,TIC types,and enhancement characteristics between the benign and malignant groups(P<0.05).DWI diag-nosed 188 cases of benign lesions and 101 cases of breast cancer with an accuracy rate of 72.66%;DCE-MRI diagnosed 179 cases of benign lesions and 110 cases of breast cancer with an accuracy rate of 66.44%;combined diagnosis yielded 203 cases of benign lesions and 86 cases of breast cancer with an accuracy rate of 87.54% (P<0.05).The AUC for DWI,DCE-MRI,and the combined diagnosis was 0.871,0.806,and 0.911,respectively,with specificities of 92.21%,89.61%,and 90.91%,and sensitivities of 85.85%,80.66%,and 92.45%,respectively.Conclusion DWI and DCE-MRI have high clinical value in distinguishing between benign breast lesions and breast cancer,and their combination promotes diagnostic accuracy.

关键词

MRI动态增强扫描/弥散加权成像/乳腺良性病变/乳腺癌/诊断价值

Key words

Dynamic contrast-enhanced MRI/Diffusion-weighted imaging/Benign breast lesions/Breast cancer/Diagnostic value

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基金项目

四川省科技计划项目(2022YJ0128)

四川省凉山州科技计划重点研发项目(22ZDYF0070)

出版年

2024
保健医学研究与实践
西南大学

保健医学研究与实践

CSTPCD
影响因子:0.512
ISSN:1673-873X
参考文献量19
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