Effects of endogenous and exogenous melatonin on obesity and research advances in its mechanisms
Obesity is a pressing global public health issue in the 21st century,associated with factors such as circadian clocks,diet,exercise,and the environment.Melatonin(MT),a multifunctional chronobiological hormone,has shown potential protective effects against obesity and is an important area of current and future research.However,systematic summariza-tion in this field is lacking.Based on previous studies,this paper focuses on the impact of endogenous MT secretion and ex-ogenous MT supplementation on obesity,and the mechanisms by which MT influences obesity,to provide a reference for future in-depth research.
MelatoninObesityLeptinAdipokinesMechanism of action