Analysis of incidence,mortality,and disease burden trends of liver cancer in Jiulongpo District,Chongqing,from 2011 to 2021
Objective To analyze the characteristics and trends of liver cancer burden in Jiulongpo district,Chongqing,and provide suggestions for liver cancer prevention and control.Methods Data on liver cancer incidence and mortality from 2011 to 2021 in Jiulongpo District were collected.Incidence rate,age-standardized rate of incidence by Chinese standard popula-tion (ASRIC),mortality rate,age-standardized rate of incidence by world standard population (ASRIW),disability-adjusted life years (DALY),years of life lost (YLL),and years lived with disability (YLD) were calculated and analyzed.Results In 2011,the crude incidence rate and ASRIC of liver cancer in Jiulongpo district were 28.58/100000 and 22.03/100000,respectively.By 2021,these rates had decreased to 23.00/100000 and 15.51/100000,respectively.The annual percentage change (APC) for crude incidence rate and ASRIC from 2011 to 2021 was-1.39％ (t=-1.707,P=0.122) and-2.76％ (t=-3.095,P=0.013),respectively.For males,the APC for ASRIC was-2.57％ (t=-2.823,P=0.020),but no significant trends were observed in crude incidence rates or female ASRIC (P>0.05).The incidence rates were consistently higher in males than females (P<0.05) and generally increased with age.The crude mortality rate and ASRMC in 2011 in this region were 23.23/100000 and 18.44/100000,respectively,and 21.10/100000 and 20.84/100000 in 2021,respec-tively.The APC for crude mortality rate and ASRMC from 2011 to 2021 in Jiulongpo district were 0.30％ (t=0.284,P=0.783) and 0.20％ (t=0.127,P=0.901).Regardless of gender,no significant trends were observed in crude mortality and ASRMC(P>0.05).Mortality rates were significantly higher in males than females over the years (P<0.05) and generally increased with age.In 2011,the YLD rate,YLL rate,and DALY rate in this district were 0.28,7.97,and 8.25 per 1000 person-years,respectively,and decreased to 0.21,5.99,and 6.20 per 1000 person-years by 2021.The APC for YLD rate,YLL rate,and DALY rate from 2011 to 2021 were 0.10％ (t=0.064,P=0.951),-2.27％ (t=-1.837,P=0.099),and-2.18％ (t=-1.799,P=0.106),respectively.Conclusion The burden of liver cancer in Jiulongpo district remains heavy,especially among males and the elderly,with high YLL rates being the primary reason for the heavy disease burden.
万方数据
维普
