目的 调查长沙市某高校大学生中医体质分布特点,探讨中医体质与大学生血压昼夜节律的相关性.方法 采用方便抽样方法,于2023年10月-2024年4月在长沙市某高校开展现况调查,对437名研究对象进行问卷调查、体格检查及动态血压监测.通过《中医体质调查量表》对研究对象进行中医体质判定,通过Pearson相关分析、Spearman相关分析和二元logistic分析中医体质与大学生动态血压及其昼夜节律的相关性.结果 不同体质研究对象的身体质量指数(BMI)、24 h收缩压(SBP)、昼间SBP的差异有统计学意义(P<0.05).其中24 h SBP正常高值有13人,异常13人,占总人数的5.9%;24 h舒张压(DBP)正常高值20人,异常7人,占总人数的6.2%;SBP昼夜节律呈非杓型183人,占总人数的41.9%;DBP昼夜节律呈非杓型88人,占总人数的20.1%.研究对象中,125例为平和质(28.6%),312例为偏颇体质(71.4%).相关性分析表明,部分中医体质得分(如阳虚质、血瘀质、气虚质得分)与动态血压部分指标(24 h SBP、昼间SBP、夜间SBP等)存在显著相关性(P<0.05),但相关性均较弱.二元logistic回归分析结果显示:相对于平和质,阳虚质是个体出现非杓型SBP的危险因素(OR=1.977,95%CI:1.083~3.610,P=0.027),阴虚质是个体出现非杓型DBP的保护因素(OR=0.350,95%CI:0.135~0.950,P=0.030).结论 长沙市某高校大学生群体血压昼夜节律异常情况较为严重;相对于平和质,阳虚质是SBP昼夜节律异常的危险因素,阴虚质是DBP昼夜节律异常的保护因素.
Analysis of the correlation between TCM constitution and circadian blood pressure rhythms in college students
Objective This study aimed to investigate the distribution characteristics of Traditional Chinese Medicine(TCM)constitutions among college students in Changsha and explore the correlation between TCM constitution and circadian blood pressure rhythms.Methods A convenience sampling was conducted between October 2023 and April 2024 at a university in Changsha,involving 437 students who underwent questionnaire surveys,physical examinations,and ambulatory blood pres-sure monitoring.TCM constitutions were determined using the TCM Constitution Survey Scale,and correlations between TCM constitution,ambulatory blood pressure,and circadian blood pressure rhythms were analyzed using Pearson correla-tion,Spearman correlation,and binary logistic regression.Results There were statistically significant differences in body mass index(BMI),24-hour systolic blood pressure(SBP),and daytime SBP among participants with different TCM consti-tutions(P<0.05).Among them,13 had normal high values of 24-hour SBP,and 13 had abnormal values,accounting for 5.9%of the total respondents;20 had normal high values of 24-hour diastolic blood pressure(DBP),and 7 had abnormal values,accounting for 6.2%of the total respondents;183 had non-dipping SBP diurnal rhythm,accounting for 41.9%of the total respondents;88 had non-dipper type DBP diurnal rhythm,accounting for 20.1%of the total respondents.Among the participants,125 were of a normal constitution(28.6%),and 312 were of a biased constitution(71.4%).Correlation analysis showed that some TCM constitution scores(such as yang-deficiency,blood stasis constitution,and qi-deficiency constitution)were significantly correlated with some dynamic blood pressure indicators(24-hour SBP,daytime SBP,night-time SBP;P<0.05),but the correlations were all weak.Binary logistic regression analysis results showed that compared with the normal constitution,yang-deficiency constitution is a risk factor for the occurrence of non-dipper type SBP(OR=1.977,95%CI:1.083-3.610,P=0.027),and yin-deficiency constitution is a protective factor for the occurrence of non-dipper type DBP(OR=0.350,95%CI:0.135-0.950,P=0.030).Conclusion The abnormal situation of blood pressure diurnal rhythm among college students in a university in Changsha city is quite serious;compared with the normal constitu-tion,yang-deficiency constitution is a risk factor for abnormal SBP diurnal rhythm,and yin-deficiency constitution is a pro-tective factor for abnormal DBP diurnal rhythm.