Needle knife treatment is widely used in chronic soft tissue injury diseases.Traditional needle knife treatment is performed without direct visualization,requiring a high level of anatomical knowledge and manual experience from the opera-tor,and it is difficult to avoid the risk of tissue damage due to anatomical variations.Recently,with the promotion and pop-ularization of musculoskeletal ultrasound,the application of ultrasound-guided visual needle knife treatment in chronic soft tissue injuries has become increasingly widespread.This article reviews the relevant literature on the application of musculo-skeletal ultrasound in needle knife treatment in recent years,combined with the author's clinical experience,and briefly ex-plains the importance of musculoskeletal ultrasound in needle knife treatment,aiming to promote further application of mus-culoskeletal ultrasound in needle knife treatment.