Effect of exercise training on exercise tolerance in acute myocardial infarction patients Post-PCI
Objective To explore the effect of exercise training(ET)on improving exercise tolerance in acute myocardial in-farction(AMI)patients after percutaneous coronary intervention(PCI),providing reference for clinical interventions.Meth-ods Overall,40 patients diagnosed with AMI and undergoing PCI at Suining Central Hospital between October 2022 and October 2023 were selected.Patients were randomly allocated to control and intervention groups,each with 20 patients.Both groups received standard medication,while the intervention group additionally received ET intervention.Exercise toler-ance was assessed at different time points[T0,4 weeks(T1),8 weeks(T2),and 12 weeks(T3)post-intervention]using peak oxygen uptake(VO2peak),anaerobic threshold metabolic equivalents,slope of ventilatory equivalent for carbon dioxide(VE/VCO2 slope),cardiac output(CO),cardiac index(CI),stroke volume(SV),stroke volume index(SVI),as well as the 36-Item Short-Form Health Survey(SF-36)quality of life scale and Borg scores.Results The intervention group showed significantly higher VO2peak at T1,T2,and T3 compared to T0,and VO2peak at T3 was significantly higher than that in the control group(P＜0.05).Anaerobic threshold metabolic equivalents were significantly higher in the intervention group at T2 and T3 compared to T0 and the control group at the same time points(P＜0.05).The control group showed significantly lower anaerobic threshold metabolic equivalents at T1 compared to T0(P＜0.05).No significant differences were observed in VE/VCO2 slope within and between groups(P＞0.05).CO and CI were significantly higher in the inter-vention group at T3 compared to T0 and the control group at the same time points(P＜0.05).SV was significantly higher in the intervention group at T3 compared to T0 and the control group at T1,T2,and T3(P＜0.05).SVI was significantly higher in the intervention group at T3 compared to T0 and the control group at the same time points(P＜0.05).The SF-36 scores at different time points in the two groups were significantly higher than T0,and the intervention group was signifi-cantly higher than the control group at T2 and T3(P＜0.05).Borg scores at different time points in the two groups were significantly lower than T0,and the intervention group was significantly lower than the control group at the same time point(P＜0.05).Conclusion ET significantly improves exercise tolerance in AMI patients post-PCI,and raises their quality of life,making it worthy of clinical application.
万方数据
维普
