ALBI and PALBI scores for predicting prognosis in sepsis patients
Objective To explore the predictive value of Albumin-Bilirubin(ALBI)and Platelet-Albumin-Bilirubin(PALBI)scores for the prognosis of sepsis patients,aiming to provide a reference for clinical decision-making.Methods A total of 163 sepsis patients admitted to a hospital in Chongqing from August 2017 to December 2021 were selected as the study par-ticipants,who were assigned to a survival group(n=82)and a death group(n=81)based on their outcomes within 28 days.Pre-treatment laboratory indicators of the patients were collected.ALBI and PALBI scores were calculated respective-ly.The predictive value of ALBI and PALBI scores for the prognosis of sepsis patients was evaluated using the Receiver Op-erating Characteristic(ROC)curve.A multivariate logistic regression analysis was used to explore the influencing factors of the prognosis of sepsis patients.Results The ALBI and PALBI scores of the death group were(-1.48±0.12)points and(-1.75±0.10)points,respectively,which were significantly higher than those of the survival group,(-2.07±0.09)points and(-2.02±0.08)points(P＜0.05).The area under the curve(AUC)of ALBI and PALBI scores for predicting the prognosis of sepsis patients were 0.783(95％CI:0.738-0.833)and 0.841(95％CI:0.796-0.891),respectively,and the combined prediction AUC was 0.926(95％CI:0.881-0.976).No statistically significant differences were ob-served in gender,age,body mass index,proportion of patients with cardiovascular diseases,endocrine diseases,kidney dis-eases,digestive system diseases,white blood cell count,hemoglobin,arterial blood oxygen partial pressure(PaO2),aspar-tate aminotransferase(AST),and alanine aminotransferase(ALT)between the two groups(P＞0.05).The Acute Physi-ology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)score,Sequential Organ Failure Assessment(SOFA)score,C-re-active protein(CRP),and total bilirubin(TBIL)levels in the death group were significantly higher than those in the survival group(P＜0.05),while platelet count(PLT)and albumin(ALB)levels were significantly lower in the death group(P＜0.05).The multivariate regression analysis showed that high APACHE Ⅱ score(OR=2.494,95％CI:1.372-4.535),high TBIL level(OR=3.184,95％CI:1.687-6.008),high ALBI score(OR=3.854,95％CI:2.082-7.131),and high PALBI score(OR=3.536,95％CI:1.859-6.725)were risk factors for the prognosis of sepsis patients(P＜0.05).Con-clusion ALBI and PALBI scores have good predictive value for the prognosis of sepsis patients,both are influencing factors for the prognosis of these patients,and combined detection has a higher predictive value for the prognosis.
万方数据
维普
