Corneal wound healing after refractive surgery:progress in biomarker research and ancillary imaging examination
Corneal refractive surgery has become one of the common treatment methods for correcting vision problems such as myopia,hyperopia,and astigmatism.However,the postoperative corneal wound healing process is complex,involving multiple stages such as inflammatory responses,cell migration,and matrix remodeling.The cornea has unique biological properties,with various cytokines and proteases participating in the regulation of wound healing,promoting corneal tissue repair,and maintaining the optical transparency and stability of the cornea.Therefore,a deeper understanding of the corneal wound healing process,the identification of related biomarkers,and the use of modern medical imaging technology for more accurate and timely monitoring of corneal wound recovery can strengthen the assessment of the ocular surface immune-in-flammatory status of patients after refractive surgery and facilitate the prevention and treatment of postoperative complica-tions.This article summarizes the role of various cytokines and proteases in corneal wound healing and discusses the applica-tion of modern imaging technology in corneal wound healing research,aiming to provide a reference for clinical practice.