保健医学研究与实践2024,Vol.21Issue(9) :73-77.DOI:10.11986/j.issn.1673-873X.2024.09.12

超声引导下聚桂醇注射治疗子宫瘢痕妊娠的疗效观察

Observation on the efficacy of lauromacrogol injection for cesarean scar pregnancy under ultrasound guidance

寇菲 韩紫娜 姚秀玲 张萌萌 马素红 韩冰 孙旺
保健医学研究与实践2024,Vol.21Issue(9) :73-77.DOI:10.11986/j.issn.1673-873X.2024.09.12

超声引导下聚桂醇注射治疗子宫瘢痕妊娠的疗效观察

Observation on the efficacy of lauromacrogol injection for cesarean scar pregnancy under ultrasound guidance

寇菲 1韩紫娜 1姚秀玲 1张萌萌 2马素红 2韩冰 2孙旺3
扫码查看

作者信息

  • 1. 河北省衡水市第二人民医院妇科,河北 衡水 053000
  • 2. 河北省衡水市第二人民医院超声科,河北 衡水 053000
  • 3. 河北医科大学附属第二医院妇科,石家庄 050000
  • 折叠

摘要

目的 探讨子宫动脉介入栓塞术(UAE)和超声引导下聚桂醇注射治疗子宫瘢痕妊娠(CSP)的疗效比较,以期为临床治疗提供参考.方法 选取2021年2月-2023年2月河北省衡水市第二人民医院收治的CSP患者220例为研究对象,采用随机数字表法将患者分为对照组(n=110)与观察组(n=110).对照组患者采用UAE治疗,观察组患者采用超声引导下聚桂醇注射治疗.于术后1 d评定2组患者临床总有效率;比较2组患者术中出血量、住院时间、手术时间、月经恢复正常时间及术后排卵恢复时间;比较2组患者治疗期间及随访1年内不良反应发生情况.结果 观察组患者总有效率为95.45%(105/110),高于对照组的89.09%(98/110),差异有统计学意义(P<0.05).观察组患者月经恢复正常时间及术后排卵恢复时间均短于对照组,差异均有统计学意义(P<0.05).2组患者治疗期间不良反应发生率比较,差异无统计学意义(P>0.05).随访1年内观察组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05).结论 相较于UAE,超声引导下聚桂醇注射治疗CSP疗效更佳,可有效降低患者术中出血量,缩短手术时间、住院时间、月经恢复正常时间、术后排卵恢复时间等,其远期疗效更优.

Abstract

Objective To compare the efficacy of uterine artery embolization(UAE)and lauromacrogol injection for cesarean scar pregnancy(CSP)under ultrasound guidance,providing a reference for clinical treatment.Methods A total of 220 CSP patients admitted to the Second People's Hospital of Hengshui between February 2021 and February 2023 were randomly as-signed to a control group(n=110)and an observation group(n=110)using a random number table.The control group un-derwent UAE,while the observation group received lauromacrogol injection under ultrasound guidance.The overall re-sponse rate was assessed one day postoperatively.Intraoperative blood loss,hospital stay,time of operation,time to re-sumption of normal menstruation,and time to postoperative ovulation recovery were compared between the two groups.Additionally,adverse reactions or events during treatment and within one year of follow-up were recorded.Results The o-verall response rate in the observation group was significantly higher than that in the control group[95.45%(105/110)vs.89.09%(98/110);P<0.05].The observation group demonstrated shorter time to resumption of normal menstruation,and time to postoperative ovulation recovery compared to the control group(P<0.05).No significant difference was found in adverse reaction rates during treatment between the two groups(P>0.05).However,the overall adverse reaction rate within one year of follow-up in the observation group was significantly lower than in the control group(P<0.05).Conclu-sion Compared to UAE,ultrasound-guided lauromacrogol injection for CSP shows superior efficacy,effectively reducing intraoperative blood loss,shortening time of operation and hospital stay,and time to resumption of normal menstruation,and time to postoperative ovulation recovery.Its long-term efficacy is also superior.

关键词

子宫瘢痕妊娠/超声引导/子宫动脉介入栓塞/清宫术/聚桂醇

Key words

Cesarean scar pregnancy/Ultrasound guidance/Uterine artery embolization/Curettage/Lauromacrogol

引用本文复制引用

出版年

2024
保健医学研究与实践
西南大学

保健医学研究与实践

CSTPCD
影响因子:0.512
ISSN:1673-873X
段落导航相关论文