首页|超声引导下聚桂醇注射治疗子宫瘢痕妊娠的疗效观察

超声引导下聚桂醇注射治疗子宫瘢痕妊娠的疗效观察

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目的 探讨子宫动脉介入栓塞术(UAE)和超声引导下聚桂醇注射治疗子宫瘢痕妊娠(CSP)的疗效比较,以期为临床治疗提供参考.方法 选取2021年2月-2023年2月河北省衡水市第二人民医院收治的CSP患者220例为研究对象,采用随机数字表法将患者分为对照组(n=110)与观察组(n=110).对照组患者采用UAE治疗,观察组患者采用超声引导下聚桂醇注射治疗.于术后1 d评定2组患者临床总有效率;比较2组患者术中出血量、住院时间、手术时间、月经恢复正常时间及术后排卵恢复时间;比较2组患者治疗期间及随访1年内不良反应发生情况.结果 观察组患者总有效率为95.45%(105/110),高于对照组的89.09%(98/110),差异有统计学意义(P<0.05).观察组患者月经恢复正常时间及术后排卵恢复时间均短于对照组,差异均有统计学意义(P<0.05).2组患者治疗期间不良反应发生率比较,差异无统计学意义(P>0.05).随访1年内观察组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05).结论 相较于UAE,超声引导下聚桂醇注射治疗CSP疗效更佳,可有效降低患者术中出血量,缩短手术时间、住院时间、月经恢复正常时间、术后排卵恢复时间等,其远期疗效更优.
Observation on the efficacy of lauromacrogol injection for cesarean scar pregnancy under ultrasound guidance
Objective To compare the efficacy of uterine artery embolization(UAE)and lauromacrogol injection for cesarean scar pregnancy(CSP)under ultrasound guidance,providing a reference for clinical treatment.Methods A total of 220 CSP patients admitted to the Second People's Hospital of Hengshui between February 2021 and February 2023 were randomly as-signed to a control group(n=110)and an observation group(n=110)using a random number table.The control group un-derwent UAE,while the observation group received lauromacrogol injection under ultrasound guidance.The overall re-sponse rate was assessed one day postoperatively.Intraoperative blood loss,hospital stay,time of operation,time to re-sumption of normal menstruation,and time to postoperative ovulation recovery were compared between the two groups.Additionally,adverse reactions or events during treatment and within one year of follow-up were recorded.Results The o-verall response rate in the observation group was significantly higher than that in the control group[95.45%(105/110)vs.89.09%(98/110);P<0.05].The observation group demonstrated shorter time to resumption of normal menstruation,and time to postoperative ovulation recovery compared to the control group(P<0.05).No significant difference was found in adverse reaction rates during treatment between the two groups(P>0.05).However,the overall adverse reaction rate within one year of follow-up in the observation group was significantly lower than in the control group(P<0.05).Conclu-sion Compared to UAE,ultrasound-guided lauromacrogol injection for CSP shows superior efficacy,effectively reducing intraoperative blood loss,shortening time of operation and hospital stay,and time to resumption of normal menstruation,and time to postoperative ovulation recovery.Its long-term efficacy is also superior.

Cesarean scar pregnancyUltrasound guidanceUterine artery embolizationCurettageLauromacrogol

寇菲、韩紫娜、姚秀玲、张萌萌、马素红、韩冰、孙旺

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河北省衡水市第二人民医院妇科,河北 衡水 053000

河北省衡水市第二人民医院超声科,河北 衡水 053000

河北医科大学附属第二医院妇科,石家庄 050000

子宫瘢痕妊娠 超声引导 子宫动脉介入栓塞 清宫术 聚桂醇

2024

保健医学研究与实践
西南大学

保健医学研究与实践

CSTPCD
影响因子:0.512
ISSN:1673-873X
年,卷(期):2024.21(9)