首页|肺超声评分联合降钙素原对感染性肺炎患儿病情的评估价值

肺超声评分联合降钙素原对感染性肺炎患儿病情的评估价值

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目的 探讨肺超声评分(LUS)联合降钙素原(PCT)对感染性肺炎(IPN)患儿病情的评估价值,以期为临床治疗提供参考.方法 选取2021年6月-2023年6月延安大学第四附属医院收治的IPN患儿115例作为研究对象.根据病情严重程度将115例IPN患儿分为轻症组(n=42)和重症组(n=73).收集患儿的临床资料及检验结果,包括性别、年龄、感染类型、发热天数等基础资料,以及血常规、C反应蛋白(CRP)、中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR).采用受试者工作特征(ROC)曲线分析LUS评分联合PCT水平对IPN病情的评估价值;采用多因素logistic回归分析探讨IPN患儿病情的影响因素.结果 重症组患儿LUS评分、PCT水平高于轻症组,差异均有统计学意义(P<0.05).LUS 评分、PCT 水平评估 IPN 病情的曲线下面积(AUC)分别为 0.791(95%CI:0.746~0.841)、0.837(95%CI:0.792~0.887),LUS评分联合PCT水平评估IPN病情的AUC为0.953(95%CI:0.908~0.998).多因素logistic回归分析结果显示:发热天数≥4.5 d(OR=2.056,95%CI:1.243~3.403),CRP≥21.08 mg/L(OR=2.303,95%CI:1.327~3.994),LUS 评分 ≥19.0 分(OR=2.901,95%CI:1.756~4.791),PCT≥3.48 ng/mL(OR=3.056,95%CI:1.905~4.901)是IPN患儿病情的独立危险因素(P<0.05).结论 高LUS评分和高水平PCT是IPN患儿病情的危险因素,LUS评分联合PCT水平可作为评估IPN患儿病情的重要指标,且联合应用评估效能更佳.
Assessment value of lung ultrasound score combined with procalcitonin level in children with infectious pneumonia
Objective To explore the assessment value of lung ultrasound score(LUS)combined with procalcitonin(PCT)in the condition of children with infectious pneumonia(IPN),in order to provide a reference for clinical treatment.Methods A total of 115 children with IPN treated at the Fourth Affiliated Hospital of Yan'an University from June 2021 to June 2023 were selected as the study participants.According to the severity of the condition,the 115 children with IPN were allocated to a mild group(n=42)and a severe group(n=73).The children's clinical data and test results were collected,including basic information such as gender,age,type of infection,and number of fever days,as well as routine blood test,C-reactive protein(CRP),neutrophil-to-lymphocyte ratio(NLR),and platelet-to-lymphocyte ratio(PLR).The receiver operating characteristic(ROC)curve analysis was used to as-sess the value of LUS score combined with PCT level in IPN condition;multifactorial logistic regression analysis was used to explore the influencing factors of IPN children's condition.Results The LUS scores and PCT levels in the severe group were signifi-cantly higher than those in the mild group(P<0.05).The areas under the curve(AUC)for assessing IPN condition by LUS score and PCT level were 0.791(95%CI:0.746-0.841)and 0.837(95%CI:0.792-0.887),respectively.The AUC for assessing IPN condition by LUS score combined with PCT level was 0.953(95%CI:0.908-0.998).The results of multifactorial logistic regression analysis showed that fever duration≥4.5 days(OR=2.056,95%CI:1.243-3.403),CRP≥21.08 mg/L(OR=2.303,95%CI:1.327-3.994),LUS score≥19.0 points(OR=2.901,95%CI:1.756-4.791),and PCT≥3.48 ng/mL(OR=3.056,95%CI:1.905-4.901)were independent risk factors for children with IPN(P<0.05).Conclusion High levels of LUS score and PCT are risk factors for IPN condition,and LUS score com-bined with PCT level can be used as an important indicator for assessing the condition of children with IPN,with better as-sessment efficacy when used in combination.

Lung ultrasound scoreProcalcitoninInfectious pneumoniaAssessment value

高佳宇、张建蕾、李利霞、王江鹏、刘学琳

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延安大学第四附属医院/延安市人民医院超声诊断科,陕西 延安 716000

延安大学第四附属医院/延安市人民医院儿科,陕西 延安 716000

肺超声评分 降钙素原 感染性肺炎 评估价值

2024

保健医学研究与实践
西南大学

保健医学研究与实践

CSTPCD
影响因子:0.512
ISSN:1673-873X
年,卷(期):2024.21(9)