Predictive value of red blood cell distribution width/platelet count ratio for prognosis of hyperbaric oxygen therapy in sudden sensorineural hearing loss
Objective To explore the predictive value of the red blood cell distribution width/platelet count ratio(RPR)for the prognosis of hyperbaric oxygen therapy in patients with sudden sensorineural hearing loss(SSHL),aiming to provide a reference for clinical decision-making.Methods A total of 127 SSHL patients treated at a hospital in Fuyang from March 2021 to February 2024 were selected as the SSHL group,and they were assigned to a good prognosis group(n=92)and a poor prognosis group(n=35)based on the outcome of hyperbaric oxygen therapy.Additionally,150 healthy individuals un-dergoing routine health checkups during the same period were selected as the control group.The red blood cell distribution width(RDW),platelet count(PLT),and RPR were measured.Receiver operating characteristic(ROC)curves were used to assess the predictive value of RDW,PLT,and RPR for the prognosis of hyperbaric oxygen therapy in SSHL patients.Multivariate logistic regression analysis was performed to explore the factors influencing the treatment prognosis of the pa-tients.Results The RDW and RPR levels in the SSHL group were higher than those in the control group,while the PLT levels in the SSHL group were lower than those in the control group,with statistically significant differences(P<0.05).The RDW and RPR levels in the poor prognosis group were significantly higher than those in the good prognosis group,and the PLT level was significantly lower in the poor prognosis group(P<0.05).The area under the curve(AUC)for RDW,PLT,and RPR in predicting the prognosis of hyperbaric oxygen therapy in SSHL patients were 0.851(0.799-0.903),0.744(0.692-0.796),and 0.902(0.799-0.953),respectively.Univariate analysis showed that in the poor prognosis group,the proportion of patients aged≥60 years,with a history of diabetes,with total deafness or flat descending type hearing loss,with severe hearing damage,and with a time from onset to hospital admission≥3 days was significantly high-er than in the good prognosis group(P<0.05).Regression analysis indicated a history of diabetes,total deafness type,se-vere hearing damage,and RPR≥0.09 were independent risk factors for poor prognosis in SSHL patients treated with hy-perbaric oxygen therapy(P<0.05).Conclusion RPR levels are closely associated with the prognosis of hyperbaric oxygen therapy in SSHL patients,and this indicator can serve as an important predictor for the prognosis of hyperbaric oxygen ther-apy in these patients.
Red blood cell distribution width/platelet count ratioSudden sensorineural hearing lossHyperbaric oxygenPrognosis
万方数据
维普
