Objective To understand the epidemiological and etiological characteristics of bacillary dysentery in Futian district,Shenzhen,so as to provide scientific basis for local disease prevention,control,and clinical treatment.Methods A descriptive epidemiological analysis of bacillary dysentery data in Futian district,Shenzhen from 2013 to 2022 was conducted to understand its epidemic seasons and population distribution characteristics.The surveillance strains were detected and analyzed to understand their drug resistance and virulence.Results The overall bacillary dysentery epidemic in Futian district showed a downward trend from 2013 to 2022,with the incidence rate decreased from 60.81/100 000 in 2013 to 16.96/100 000 in 2022.The peak period of bacillary dysentery in Futian district was from June to August in summer.The highest incidence rate was among children living at home under 5 years old.Pathogenic monitoring showed that the detection rate of bacillary dysentery-positive strains was 6.04％(126/2 086).Shigella flexneri was the dominant strain,accounting for 55.56％(70/126),followed by Shigella sonnei,accounting for 44.44％(56/126).Drug resistance testing of 126 strains of Shigella showed that the top three antibiotics with the highest drug resistance rates were nalidixic acid(94.44％),ampicillin(89.68％),and gentamicin(48.41％).Virulence gene testing showed that the top three virulence genes with the highest detection rates were ipaH(99.21％),setlA(92.06％),and virA(90.48％).Conclusions The test results of drug resistance and virulence genes show that bacillary dysentery still has strong pathogenicity and has the risk of causing outbreaks and epidemics.Surveillance and management of bacillary dysentery should continue to be strengthened.
NETL
NSTL
万方数据
