Objective To summarize the essential operations of'Tianji'orthopaedic robot during percutaneous vertebroplasty(PVP)in treatment of osteoporotic thoracolumbar compression fractures,and to analyse the learning curve.Methods Fifty cas-es of osteoporotic thoracolumbar compression fractures treated with PVP assisted by a'Tianji'orthopaedic robot from August 2018 to August 2019 were retrospectively analyzed.Image acquisition time and planning time were recorded,and the learning curve of the orthopedic robot system operated by clinician was analyzed.Results When 12 surgical cases were completed,the image acquisition time changed and was maintained at(23.6±3.2)min.When operations amounted to 20 surgical cases,the plan-ning time was significantly reduced and maintained at(1.5±0.2)min.When the surgical cases increased,the image acquisition time and planning time decreased and entered the plateau period.According to the above learning curve analysis results,the first 20 cases were divided into novice group,and the 21st to 50th cases proficiency group.The image acquisition time and plan-ning time of the proficiency group were shorter than that of the novice group,and the proportion of patients with bone cement leakage was lower than that of the novice group,the differences of two groups is statistically significant(P<0.05).Image acquisi-tion time was longer for patients with thoracic fractures body of mass index 25 kg/m2,the planning time was longer for patients with thoracic fracture and 2 vertebral fractures of body mass index 25 kg/m2,and the differences of those patients were statisti-cally significant(P<0.05).Conclusion The plateau period of the learning curve of'Tianji'orthopedic robot is about 20 cases.The surgeon and assistant need to continuously improve and perfect the preoperative preparation,master the image acquisition and path-planning operation,so as to improve the operation efficiency,shorten the operation time and reduce the occurrence of complications.