Investigation on Chronic Kidney Disease in Native Tibetan Adults Living in High-Altitude Areas
Objective:To investigate the prevalence and risk factors of Chronic Kidney Disease(CKD)among native Tibet-an adults living in Niangre Township,Lhasa City(elevation 3 700 m)and Pumajiangtang Township,Shannan City(elevation 5 373 m),Tibet.Providing fundamental data for CKD prevention and control in Tibet.Method:From August 2022 to October 2023,a total of 430 native Tibetan adults aged 18 years and above living in NinagRe Township,Lhasa City,and Pumajiangtang Township,Shannan City were selected using a stratified ran-dom sampling method.They underwent questionnaire survey,physical examinations,and biochemical tests relat-ed to chronic kidney disease.Result:Among the 430 native Tibetan adults living in Niangre Township,Lhasa City,and Pumajiangtang Township,Shannan City,109 were diagnosed with CKD,resulting in a prevalence of 25.3%.The CKD prevalence in Pumajiangtang Township(40.8%)was significantly higher than that in Niangre Township(11.2%)(P<0.05).The prevalence of CKD increased with age,with a higher rate in females(32.2%)compared to males(17.3%).The prevalence was also higher in individuals who consumed alcohol(36.0%)com-pared to non-drinkers(22.1%).At an altitude of 3 700 m,kidney damage mainly manifested as renal function de-cline,whereas at an altitude of 5 300 m,it primarily manifested as hematuria.The majority of CKD cases were in stage 1 to 2.Multivariate unconditional logistic regression analysis indicated that high altitude,female gender,age≥51 years,and alcohol consumption were risk factors for CKD.Conclusion:The prevalence of CKD in Nian-gre Township,Lhasa City,and Pumajiangtang Township,Shannan City,are relatively high.Altitude,gender,age,and alcohol consumption are the main influencing factors for CKD prevalence.
NETL
NSTL
万方数据
