A Study on the Prevalence and Influencing Factors of Primary Hypertension Complicated with Hyperuricemia in the Tibet Region
Objective:To explore the prevalence and influencing factors of hyperuricemia(HUA)in hypertensive patients in the Tibet region.Methods:A retrospective analysis was conducted on 301 hypertensive patients ad-mitted to the cardiology department of a tertiary hospital in the Tibet Autonomous Region from January to Decem-ber 2018.Patients were divided into two groups based on the presence of hyperuricemia:the non-HUA group(117 cases)and the HUA group(184 cases).Demographic data,comorbidities,physical examinations,and bio-chemical indicators of the two groups were collected and compared.Multifactorial Logistic regression analysis was used to explore the relationship between HUA and hypertensive patients.Results:The prevalence of HUA in the hypertensive population in Tibet was 61%(184/301),including 132(71.7%)males and 52(28.3%)fe-males,74(40.2%)Tibetans and 110(59.8%)Han nationality,with statistically significant differences(P<0.05).Han Chinese(OR=5.720,95%CI:2.174∼15.048),alcohol consumption(OR=3.165,95%CI:1.331∼7.525),obesity(OR=2.977,95%CI:1.157∼7.664),high HB(OR=3.069,95%CI:1.202∼7.836),hypertriglyceridemia(OR=2.466,95%CI:1.065∼5.707),low HDL-C(OR=2.610,95%CI:1.147∼5.939),diuretics(OR=3.221,95%CI:1.444 ∼ 7.187),urea(OR=1.649,95%CI:1.251 ∼ 2.173),and SCR(OR=1.039,95%CI:1.013 ∼1.065)were risk factors for developing HUA in hypertension,and women(OR=0.444,95%CI:0.199∼0.988)were protective factors.Conclusion:The prevalence of hypertensive HUA is high in Tibet,and HUA patients are predominantly male and Han nationality.Obesity,alcohol consumption,high HB,abnormal creatinine,abnor-mal urea nitrogen,hypertriglyceridemia,low HDL,and diuretic drug use may be risk factors for HUA in hyper-tensive patients.
Tibet regionhypertensionhyperuricemiainfluencing factors