Research advances of heterologous synthesis of monoterpenes in Saccharomyces cerevisiae
Monoterpenes are widely used in food, medicine and industries, which have great economical values. With the development of synthetic biology, monoterpenes synthesis using microbial cell as factory have become a hot research topic. Saccharomyces cerevisiae is a model eukaryotic expression strain, mevalonate pathway provides precursors for the synthesis of monoterpenes, so it has great advantages to construct heterologous monoterpenes synthesis pathway. The construction of heterologous monoterpenes synthesis pathway in Saccharomyces cerevisiae was introduced. The research advances in heterologous expression of monoterpenes in Saccharomyces cerevisiae were reviewed from regulatory mechanisms of metabolic flux of mevalonate pathway and regulation of enzyme catalytic efficiency using fusion enzymes.
国家科技期刊平台
NSTL
万方数据
维普
