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口腔和肠道微生物群落与关节炎疾病的相关性研究

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人体是由细胞和微生物共同组成的综合生物体,人体内的微生物主要分布在皮肤、黏膜和腔道中。而口腔和肠道作为腔道和黏膜的重要组织,分别拥有人体的第一和第二大微生物群落,含有各种细菌、真菌和病毒菌群。正常的口腔和肠道微生物群落能维持身体的平衡运行状态,而这些微生物群一旦失调,则会引发人体各类疾病。其中,关节炎疾病就是一种常见的慢性炎症。在医学专家的长期研究中发现,关节炎疾病与人体口腔和肠道微生物群落中的菌株失灵有关。因此,研究二者之间的作用机制和相关性具有实际意义。
A Study on the Correlation between Oral and Intestinal Microbial Communities and Arthritis Diseases
The human body is a comprehensive organism composed of cells and microorganisms.The microorganisms in the human body are mainly distributed in the skin,mucosa,and lumen,while the oral cavity and intestine,as important tissues of the lumen and mucosa,respectively,have the first and second largest microbial communities in the human body,containing various bacterial,fungal,and viral microbiota.The normal oral and intestinal microbiota can maintain a balanced operation of the body,and once these microbiota are dysregulated,it can cause various diseases in the human body.Among them,arthritis is a common chronic inflammation.In long-term research by medical experts,it has been found that arthritis is related to the failure of bacterial strains in the human oral and intestinal microbiota.Therefore,studying the mechanism of action and correlation between the two has practical

oral microbiotaIntestinal microbiotaArthritis diseaserelativity

王高强

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郑州澍青医学高等专科学校,河南 郑州 450064

口腔微生物群落 肠道微生物群落 关节炎疾病 相关性

2024

工业微生物
全国工业微生物信息中心 上海市工业微生物研究所

工业微生物

影响因子:0.293
ISSN:1001-6678
年,卷(期):2024.54(1)
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