Study on the In Vitro Antibacterial Activity of 21 Traditional Chinese Medicine Extracts
The paper evaluates the in vitro antibacterial effects of 21 traditional Chinese medicine ethanol extracts on Staphylococcus aureus,Bacillus subtilis,Pseudomonas aeruginosa,and Escherichia coli.The traditional Chinese medicine ethanol extract was prepared by ethanol reflux method.The antibacterial activity of 21 extracts of Chinese herbs was determined by double gradient dilution method.Among the 21 ethanol extracts of traditional Chinese medicine,Pseudomonas aeruginosa and Escherichia coli showed no significant antibacterial activity.However,13 ethanol extracts including honeysuckle,Rhodiola,and rhubarb showed significant antibacterial activity against Staphylococcus aureus,with a MIC range of 0.84-14.92 mg/mL;Among them,honeysuckle has the best antibacterial effect,with a MIC of 0.84 mg/mL;Eight ethanol extracts,including honeysuckle,platycodon grandiflorus,and Qinpi,have significant antibacterial activity against Bacillus subtilis,with a MIC range of 3.54-17.96 mg/mL;Among them,the ash bark has the best antibacterial effect,with a MIC of 3.54 mg/mL.Among the 21 ethanol extracts of traditional Chinese medicine,honeysuckle,Rhodiola,rhubarb,Platycodon grandiflorus,and the ash bark have the best antibacterial effects,and their antibacterial effects on Gram-positive bacteria are better than those on Gram-negative bacteria.
traditional Chinese medicineextractsStaphylococcus aureusBacillus subtilisPseudomonas aeruginosaEscherichia coliantibacterial activity
万方数据
维普
