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金属蛋白酶对雏鸡生理、生化水平的影响

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为了研究金属蛋白酶在饲料添加剂中的安全性,本实验采用临床有效治疗量 1 mg/kg体重的1倍(低剂量组)、3倍(中剂量组)以及 5 倍(高剂量组)量饮水,灌服 8 日龄健康雏鸡,对试验组增重、采食量、生理生化指标以及肝肾功能进行研究.结果表明:中、高剂量组与空白对照组相比,鸡只在给药期间有所增重.病理切片结果显示,各组鸡的脏器正常.上述结果说明雏鸡对金属蛋白酶具有良好的耐受性.
Effects of Metalloproteases on the Physiological and Biochemical Levels of Chicks
In order to investigate the safety of metalloproteinases in feed additives,8-day-old healthy chicks were fed with 1 times(low dose group),3 times(medium dose group)and 5 times(high dose group)of 1 mg/kg body weight.Weight gain,feed intake,physiological and biochemical indexes,liver and kidney function of the experimental group were studied.The results showed that chickens gained weight during administration compared with the neutral and high-dose groups compared with the blank control group.The pathological section results showed that the organs of the chickens in each group were normal.This indicates that chick metalloproteinases are well tolerated.

MetalloproteinasesBlood biochemical indicatorsBiosecurity

刘芳、胡鹏程、汤树生、李源、刘宁、刘鼎阔

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鼎正新兴生物技术(天津)有限公司,天津 300383

天津市企业技术中心,天津 300383

中国农业大学动物医学院,北京 100091

金属蛋白酶 血液生化指标 生物安全

天津市科技计划项目

18PTSYJC00050

2024

工业微生物
全国工业微生物信息中心 上海市工业微生物研究所

工业微生物

影响因子:0.293
ISSN:1001-6678
年,卷(期):2024.54(1)
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