In order to investigate the safety of metalloproteinases in feed additives,8-day-old healthy chicks were fed with 1 times(low dose group),3 times(medium dose group)and 5 times(high dose group)of 1 mg/kg body weight.Weight gain,feed intake,physiological and biochemical indexes,liver and kidney function of the experimental group were studied.The results showed that chickens gained weight during administration compared with the neutral and high-dose groups compared with the blank control group.The pathological section results showed that the organs of the chickens in each group were normal.This indicates that chick metalloproteinases are well tolerated.
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