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溺亡后肠道菌群变化综述

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对死后间隔时间(postmortem interval,PMI)的推断,是法医界最大的难题之一,从传统的根据尸体现象推断PMI到如今利用硅藻检验、影像学、分子生物学及人工智能等众多高新技术,极大地提高了PMI判断的准确性.人体死亡后,肠道菌群将发生剧烈变化,因此,分析肠道菌群的变化特点可以为法医鉴定提供新思路.通过肠道微生物分析,建立PMI与肠道菌群之间的关系,从而提高PMI的精确性,极大地拓展了肠道菌群的研究范畴.文章就溺亡尸体肠道菌群的时序性变化进行了简要综述,旨在探讨肠道菌群在法医实践中推断死亡时间的应用现状及应用前景.
A Review of Changes in Gut Microbiota After Drowning
The inference of postmortem interval(PMI)is one of the biggest challenges in the forensic field.The use of advanced technologies such as diatom testing,imaging,molecular biology,and artificial intelligence has greatly improved the accuracy of PMI judgment,from the traditional inference of postmortem corpses to the current one.After human death,the gut microbiota will undergo drastic changes.Therefore,analyzing the changes in gut microbiota can provide new ideas for forensic identification.By analyzing gut microbiota,the relationship between PMI and gut microbiota is established,thereby improving the accuracy of PMI and greatly expanding the scope of gut microbiota research.This paper provides a brief review of the temporal changes in gut microbiota of drowned corpses,aiming to explore the current situation and application prospects of gut microbiota in forensic practice for inferring the time of death.

forensic pathologydead bodies in waterintestinal microbiotainference of postmortem interval

马玉欣、马渊、徐胜杰、宋积寿、马琴、傅思武

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西北民族大学医学部,甘肃 兰州 730030

法医病理 水中尸体 肠道菌群 死亡时间推断

2024

工业微生物
全国工业微生物信息中心 上海市工业微生物研究所

工业微生物

影响因子:0.293
ISSN:1001-6678
年,卷(期):2024.54(1)
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