Protein tyrosine phosphatase(PTP)is as an important protein that regulates different kinds of cellular activities.Protein tyrosine phosphatase dysregulation is closely related to some common diseases including cancer,metabolic diseases,cardiovascular diseases and mental illness.Some studies have shown that the occurrence and development of these diseases can be effectively controlled by inhibiting the PTP.In this paper,the research progress on major PTP inhibitors will be reviewed according to different subtypes,in order to lay a foundation for the development of protein tyrosine phosphatase inhibitors and guide the development of related drugs.
关键词
蛋白酪氨酸磷酸酶/亚型/抑制剂/疾病
Key words
protein tyrosine phosphatase/subtype/inhibitor/disease
维普
万方数据