Research Progress of the Application of C.elegans Model in the Field of Anti-aging
As the problem of population aging is getting severe,aging and aging-related diseases have gradually become the hot research topics.The C.elegans(Caenorhabditis elegans)has the advantages of small individual size,short life cycle,rapid reproduction,clear genetic background,easy cultivation and observation,and high homology with human genes,and has been widely used in the fields of anti-aging,anti-infection,neurodegenerative disease treatment and drug screening.In this paper,the molecular mechanism of aging,the indexes for evaluating aging and the related aging models based on the C.elegans model are reviewed,in order to find new development paths in the field of anti-aging.
Caenorhabditis eleganssgingmolecular mechanismevaluation index