With the development of science and technology,biotechnology has shown great potentials in the field of pathogenic microbial therapy.The paper introduced the basic principles of biotechnology in the treatment of pathogenic microorganisms,including its applications in gene editing,biologics development and plasmid-mediated gene transfer technology.Then,the practical application cases of pathogenic microbial therapy through bioteehndogy are discussed,the future development direction is prospected,and especially the exploration of personalized treatment strategy,multidisciplinary cooperation and new technology are conducted.
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