Study on the Quality Standards of the Shuangbai Xiaozhong Zhitong Cream
The article aims to establish a quality control method for Shuangbai Xiaozhong Zhitong Cream(a anti-inflammatory and pain relieving drug).Thin layer chromatography is used to identify the Angelica sinensis tail and red peony in the formula.High performance liquid chromatography is used to determine the content of berberine hydrochloride in phellodendron in the formula.Microscopic identification is used to identify rhubarb,phellodendron,platycladus orientalis leaves,and safflower in the formula.The thin-layer chromatography method for identifying Angelica sinensis tail and red peony has strong specificity and negative results without interference.The microscopic features such as cluster crystals of rhubarb,stone cells of phellodendron,stomata of platycladus orientalis leaves,and pollen grains of safflower are all obvious.The berberine hydrochloride in phellodendron exhibits a good linear relationship between 24.92-299.1 1ng(R2=1.000 0),with an average recovery rate of 102.3％(n=9)and an SRSD of 2.6％.The results show that this method is simple,highly specific,and reproducible,and can be used as a quality standard for Shuangbai Xiaozhong Zhitong cream.
万方数据
维普
