首页|某油田工人脂肪肝检出率及其影响因素研究

某油田工人脂肪肝检出率及其影响因素研究

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目的 分析脂肪肝与BMI、血脂及尿酸的剂量—反应关系,探索脂肪肝的危险因素,为脂肪肝的防治提供参考依据.方法 采用横断面调查分析陕北地区某油田2021年度职工健康体检资料,应用二元logistic向前逐步回归模型和限制性立方样条模型分析人群脂肪肝的危险因素.结果 本研究共收集调查对象1 995人,检出脂肪肝549人,检出率为27.52%;男性检出率为35.55%,女性检出率为10.59%,脂肪肝男性检出率高于女性(x2=135.982,P<0.05);超重、肥胖人群脂肪肝检出率分别为38.66%,78.34%高于体质量正常人群9.93%(x2=458.255,P<0.05),脂肪肝人群在血糖、血脂、尿酸、肝脏酶学等生化指标上的水平高于非脂肪肝人群,差异有统计学意义(t=-16.89、-10.63、-7.15、-17.09、-5.21、-7.82、-18.05、-4.40,P<0.05);控制混杂因素的二元logistic 回归分析显示,BMI、AST、TG、HbA1c与脂肪肝的检率有显著的影响(OR=5.32、29.90、12.98、2.78、4.01,P均<0.01),肥胖是贡献最大的因素.结论 陕北地区某油田职工脂肪肝的患病风险随BMI水平升高增加,脂肪肝和糖、脂代谢紊乱密切相关.
Study on the detection rate of fatty liver disease and its influencing factors among workers in an oil field
Objective To analyze the risk factors of fatty liver and explore the dose-response relationship of body mass index,blood lipid,and uric acid,providing a reference for its prevention and treatment.Methods A cross-sectional investigation was used to analyze the health examination data of employees in an oil field in northern Shaanxi in 2021.The binary logistic regression model and restricted cubic spline model were used to analyze the risk factors of fatty liver.Results In this study,a total of 1 995 subjects were collected,and 549 were detected fatty liver,the detection rate was 27.52%;The male detection rate was 35.55%,which was significantly higher than that(10.59%)of the(x2=135.982,P<0.05);The detection rates of fatty liver in overweight and obese people were 38.66%and 78.34%,respectively,which were significantly higher than that(9.93%)of the normal weight population(x2=458.255,P<0.05).The levels of blood glucose,lipid,uric acid,liver enzymology and other biochemical indexes in fatty liver group were higher than those in non-fatty liver group,with statistically significant differences(t=-16.89,-10.63,-7.15,-17.09,-5.21,-7.82,-18.05,-4.40,P<0.05).Binary logistic regression analysis controlling for confounders showed the BMI,AST,TG,and HbA1c had significant influences on the detection of fatty liver(OR=5.32,29.90,12.98,2.78,and 4.01,respectively,P<0.01).Moreover,the restrictive cubic spline model controlling for confounders showed a positive relationship between the BMI,FPG,LDL-C,and UA and the fatty liver.Obesity is the biggest contributor.Conclusion The risk of fatty liver among workers in an oil field in northern Shaanxi increased with the increase of BMI level.Fatty liver is closely related to the disorder of sugar and lipid metabolism.

Fatty liver diseaseBody mass indexRisk factorsRestrictive cubic spline model

吴世明、党鑫、时桂新、郭花斌

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汉阴县中医医院,陕西安康 725100

长江大学医学部

脂肪肝 BMI 危险因素 限制性立方样条模型

陕西省体育局常规课题

2021001

2024

工业卫生与职业病
鞍山钢铁集团公司

工业卫生与职业病

CSTPCD
影响因子:0.486
ISSN:1000-7164
年,卷(期):2024.50(2)
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