首页|正交试验设计法优化健脾温胃胶囊的提取工艺

正交试验设计法优化健脾温胃胶囊的提取工艺

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目的:优选出健脾温胃胶囊剂的最佳提取工艺.方法:以处方中党参炔苷的含量和浸膏收率作为优选评价指标,采用正交试验设计法优选健脾温胃胶囊剂的提取工艺条件.结果:最佳提取工艺条件为加8倍量的水,回流提取3次,每次1h;采用低压真空浓缩干燥法(温度60℃,真空度在0.07 ~0.08MPa)对提取液进行浓缩、干燥.结论:最佳提取工艺条件提取效率高,稳定性和重复性好,可作为健脾温胃胶囊剂的提取工艺.
Optimization of Extraction Process of Jianpiwenwei Capsules by Orthogonal Design
Objective:To optimizate the best extraction process of Jianpiwenwai Capsules.Methods:Took the content of Lobetyolin and the extract yield as the evaluation index in the prescription of the optimum conditions of the extraction process,and the orthogonal test design as the optimized extraction conditions of Jianpiwenwai Capsules.Results:The optimum extraction conditions were as follows:added 8 times amount of water and extracted 3 times for one hour every time.Low pressure vacuum concentration and drying method (the temperature was 60 ℃,and the vacuum degree was between 0.07 ~0.08 MPa) was taken to condense and dry of the extract concentration.Conclusion:The optimum extraction conditions has high extraction efficiency,good stability and repeatability.It can be used as the extraction process of Jianpiwenwai capsules.

Orthogonal designJianpiwenwai CapsuleExtraction processLobetyolin

冯果、刘文、吴洁、张石宇、何新、吴增光

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贵阳中医学院,贵州贵阳550025

天津中医药大学,天津300193

正交设计 健脾温胃胶囊剂 提取工艺 党参炔苷

贵州省科学技术厅贵阳中医学院科学技术联合基金贵州省教育厅普通高等学校中药民族药(苗药)新剂型新制剂工程研究中心课题贵州省科技厅中药民族药炮制与制剂工程技术研究中心课题

黔科合中药字[2011] LKZ7025号黔教合KY字[2014]22号黔科合重G字[2012]4001号

2016

贵阳中医学院学报
贵阳中医学院

贵阳中医学院学报

影响因子:1.18
ISSN:1002-1108
年,卷(期):2016.38(2)
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