首页|心衰宁颗粒治疗老年高血压病合并心力衰竭的临床研究

心衰宁颗粒治疗老年高血压病合并心力衰竭的临床研究

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目的:研究心衰宁颗粒联合西医常规治疗老年高血压病合并心力衰竭患者的临床疗效和安全性.方法:将老年高血压病合并心力衰竭患者按就诊顺序随机分为观察组50例,对照组50例,对照组采用常规西医治疗,观察组在对照组基础上加用心衰宁颗粒,疗程4周,比较两组患者的中医证候疗效、心力衰竭疗效、收缩压(SBP)、舒张压(DBP)、左室舒张末期内径(LVEDD)、左室射血分数(LVEF)及血浆N-端脑利钠肽(NT-proBNP)变化.结果:两组患者治疗后比较,观察组在中医证候疗效、心力衰竭疗效、SBP、DBP、LVEDD、LVEF、NT-proBNP等方面均优于对照组,差异有统计学意义(P<0.05).结论:心衰宁颗粒联合西医常规治疗老年高血压病合并心力衰竭,疗效优于单纯西药治疗,安全性高,值得临床推广.
A Clinical Study on the Effects of Xinshuaining Pills in Treating Senile Hypertension Complicated with Heart Failure
Objective:To discuss the clinical efficacy and safety of treating patients with senile hypertension complicated with heart failure by using Xinshuaining pills combined with conventional treatment of western.Methods:100 patients with senile hypertension complicated with heart failure were divided into two groups at random:the treatment group (50) and the control group (50).The control group was given conventional western medicine therapy,while the treatment group was given Xinshuaining pills combined with conventional western medicine therapy for 4 weeks as a course of treatment.The changes in curative effect of TCM syndrome,heart failure syndrome,clinical indicators (SBP、DBP、LVEDD、LVEF and NT-proBNP)were compared.Results:After treatment,the TCM syndrome curative effect,heart failure syndrome curative effect,left ventricular ejection fraction (LVEF) and plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) levels of the treatment group were superior to those of the control group.Differences were statistical significance (P < 0.05).Conclusion:Xinshuaining pills combined conventional western medicine therapy was better than conventional western medicine therapy in treating patients with senile hypertension complicated with heart failure.It has high safety and deserves the clinical expansion.

senile Hypertensionchronic heart failureXinshuaining Pills

何远利、安祯祥、杨蕊琳、孙刚

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贵阳中医学院第一附属医院,贵州贵阳550001

老年高血压病 慢性心力衰竭 心衰宁颗粒

贵州省科技厅社会发展科技攻关计划项目

黔科合SY字[2013]3022号

2016

贵阳中医学院学报
贵阳中医学院

贵阳中医学院学报

影响因子:1.18
ISSN:1002-1108
年,卷(期):2016.38(2)
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