The Relationship Between the Gender Differences in Incidence of Depression and GR and MR Content Changes
Depression is a serious mental disease.HPA axis hyperactivity promoting the glucocorticoid content of neuroendocrine changes of depression is the most obvious cause of depression.GR and MR's balance in the hippocampus plays an important role in negative feedback regulation of the HPA axis,GR decreases and MR increases are likely to change in the pathogenesis of depression.With gender differences,the GR downward phase of women is significantly more than men,MR role in women is more than in men,and Women can improve optimism and reduce the incidence of despair and depression.National study finds depression both receptors are likely to be new targets.
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