Effects of Qingre Zhidai Extract on Animal Model of Rats with Chronic Pelvic Inflammation Disease
Objective:To investigate the effects of Qingre Zhidai extract on animal model of rats with chronic pelvic inflammation induced by phenol plasmagel and explore the roles of clearing heat and arresting leucorrhea,removing blood stasis and anti-inflammatory of this prescription so as to provide experimental basis to illustrate the clinical curative effect.Methods:The animal model of rats with chronic pelvic inflammation of induced by phenol plasmagel was made.The rats were given medicine by oral administration according to the dosage after modeling 1 day and this treatment lasted for 21 days.Then the indicators of uterine patency rate,hemorheology,uterine histopathology were tested.Methods:Qingre Zhidai extract can significantly reduce the experimental rats' blood hyperviscosity,improve hemorheology indicators,increase uterine patency rate and improve the pathological state of the uterus.Conclusions:Qingre Zhidai extract has a certain role in treating rats with chronic pelvic inflammatory disease model.Its mechanism may be related to its antipyretic,blood-stasis improving and anti-inflammatory effects.