The clinicopathological features and diagnostic difficulties of hepatic angiosarcoma
Objective To investigate the clinicopathological characteristics of hepatic angiosarcoma and analyze its diagnostic difficulties.Methods The pathological and clinical data of 6 patients diagnosed with hepatic angiosarcoma in the department of pathology of Beijing Hospital from 2013 to 2022 were retrospectively analyzed.Results The clinical manifestations and images of the 6 patients with hepatic angiosarcoma were non-specific.The morphologies were diverse.Atrophic liver cell plates and hepatic sinusoids lined with atypia cells were observed in high-grade angiosarcoma,while low-differentiated angiosarcoma was more atypical,and should be distinguished from other sarcomas.The tumor cells expressed vascular endothelial markers CD31,CD34 and ERG.Conclusion Hepatic angiosarcoma is a rare malignant tumor without specificity in clinical manifestations and image examinations.Comprehensive analyses of the clinical manifestations,morphology and immunohistochemical staining are helpful for a right pathological diagnosis.
万方数据
维普
