Study on the factors influencing the long-term efficacy of ultrasound-guided microwave ablation for recurrent liver cancer
Objective To investigate the influence factors of ultrasound-guided microwave ablation on the long-term treatment outcomes of recurrent liver cancer.Methods We collected data from 80 patients with recurrent liver cancer treated at our hospital from September 2019 to September 2021 and conducted a retrospective analysis.The patients were divided into a poor prognosis group(22 deaths)and a good prognosis group(55 survivals)based on their 1-year postoperative survival.Clinical data were compared between the two groups,including serum levels of alpha-fetoprotein(AFP),albumin(Alb),alanine aminotransferase(ALT)and aspartate aminotransferase(AST).Multiple Logistic regression analysis was conducted to identify the factors influencing the long-term efficacy of ultrasound-guided microwave ablation in patients with recurrent liver cancer.Results In the poor prognosis group,8 cases(36.36％)of patients were classified as Child-Pugh grade B,11 cases(50.00％)had multiple lesions,10 cases(45.45％)had lesion diameter ≥3 cm,and 9 cases(40.91％)had AFP ≥100 ng/mL.In comparison,the good prognosis group had 8 cases(13.79％)with Child-Pugh grade B,12 cases(20.69％)with multiple lesions,13 cases(22.41％)with lesion diameter ≥3 cm,and 10 cases(17.24％)with AFP ≥100 ng/mL.These differences were found to be statistically significant(P＜0.05).Multivariate Logistic regression analysis further confirmed that Child-Pugh grade B,multiple lesions,lesion diameter ≥3 cm,and AFP≥100 ng/mL were identified as risk factors for a poor prognosis in patients with recurrent liver cancer after ultrasus-guided microwave ablation(P＜0.05).Conclusion Ultrasound-guided microwave ablation has better long-term efficacy for patients with Child-Pugh grade A,single lesion,lesion diameter＜3 cm,and AFP＜100 ng/mL.
万方数据
维普
