Clinical characteristics,diagnosis and treatment of liver cirrhosis combined with coeliacal pleural ascites:A case series study
Objective To investigate the features,diagnosis and treatment of liver cirrhosis complicated with chylothorax and/or chylous ascites.Methods Select 4 patients with liver cirrhosis complicated with chylothorax/chylous ascites admitted to our hospital from March 2022 to March 2023,collect their characteristics and laboratory data,and give high-dose human albumin combined with somatostatin analog therapy,and observe its curative effect and prognosis.Results(1)The average age of the patients was 61±8.91 years old,and 3/4 were male;3 cases were caused by hepatitis B virus infection,1 case was alcohol;3 cases were complicated with renal insufficiency,2 cases had hypoproteinemia;2 cases The Child-Pugh classification was grade C,1 case was complicated with hepatorenal syndrome,and the MELD score was greater than 20;(2)3 cases had chylomicron appearance,and 1 case was light yellow;3 cases were positive for chylomicrons,and 3 cases were present at the same time chylothorax and ascites effusion,1 case of pleural effusion,1 case of chylous ascites;(3)After administration of large doses of human serum albumin,the effusions of four patients all subsided compared with before,and the serum creatinine improved.Patients were followed up at 1 month,3 months,and 6 months after discharge;three patients were in stable condition,and one patient died after four months of follow-up.Conclusion The treatment of patients with chylothorax/chylous ascites with high-dose albumin combined with somatostatin analogues can help the effusion subside,improve the renal function and even the quality of life of the patients.