Viscosity Responsive Near Infrared Fluorescence Probe and Its Imaging Application
Probe L was synthesized using ethyl 3-dehydroshikimate as the raw material through an aromatic condensation reaction.The structure of probe L was confirmed using magnetic resonance imaging,infrared spectroscopy and high-resolution mass spectrometry.Probe L exhibited significant fluorescence enhancement in high-viscosity solvents such as glycerol and extremely weak fluorescence in low-viscosity solvents,confirming its notable viscosity response feature.Moreover,probe L demonstrated good anti-interference capability,high pH stability and good photo-stability.Leveraging the viscosity-fluorescence response of probe L,fluorescence imaging of viscosity changes in HeLa cells induced by LPS or Nystatin was conducted.
国家科技期刊平台
NSTL
万方数据
