Clinical Effect of Sophora Alkaloids Tannate Tablets Combinedwith Antiviral Therapy on Diarrhea Associated with AIDS
Objective To observe the adjuvant treatment effect of Sophora Alkaloids Tannate tablets on AIDS patients with diarrhea and its influence on immune function.Methods The auxiliary efficacy of Sophora Alkaloids Tannate tablets was evaluated by comparing the symptom scores and the daily frequency of diarrhea between the experimental group and the control group.The changes of CD4+T cells and white blood cells before and after the treatment were compared between the two groups to observe the effect of sophora alkaloids tannate tablets on the immune function of patients before and after the treatment.Results Symptom severity grading score statistics showed that from the point of stool frequency,the effective rate of adjuvant treatment with sopho-ra alkaloids tannate tablets and simple conventional western medicine(such as octreotide,Imodil,phenytopi-dine,and etc.)in the treatment of AIDS patients with diarrhea was 83.33%and 76.67%,respectively.Accord-ing to fecal property,the effective rates of the two groups were 90%and 83.33%respectively.The effective rate of abdominal pain treatment in both groups was 43.33%.From the improvement of stool frequency,the reduction degree of the score after the adjuvant treatment with sophora alkaloids tannate tablets was significantly greater than that of the conventional western medicine group.There were no significant differences between the two treatments in terms of stool quality and abdominal pain.Immunological analysis showed that the number of CD4+T lymphocytes and white blood cells increased slightly both with the adjuvant treatment of sophora alkaloids tan-nate tablets and with conventional western medicine.Among them,CD4+T cells were significantly increased,and the difference was statistically significant,The elevation of white blood cells was not significant,and the difference was not statistically significant.Conclusion The effect of Sophora alkaloids tannate tablets is better than that of conventional western medicine in the treatment of AIDS patients with diarrhea.It can be used as an auxiliary means in the process of AIDS antiviral treatment.